OncoAlly™ Cancer Predisposition

Test Code – OA010

Test Description

OncoAlly™ Cancer Predisposition uses a whole genome sequencing platform to analyze 87 genes for genetic variants associated with hereditary cancers.

*This is an optional analysis when ordering OncoAlly™ Solid Tumor Analysis.

When to Order

Order this test when a patient has a medical or family history suggestive of one or more hereditary cancer predisposition syndromes or when germline variant analysis for hereditary cancer predisposition is necessary to guide medical management.

Included Analyses

  • Sequence analysis of hereditary cancer-associated genes (single nucleotide variants, deletions, insertions, and characterized intronic variants)
  • Copy number variant analysis of hereditary cancer-associated genes (duplications/deletions, mobile element insertions, and inversions)

Included Genes:

Note: The PMS2 gene contains regions that are non-unique, therefore not all variants can be assigned to the correct location, limiting interpretation.

View a list of cancers associated with each gene.

Test Performance

Sensitivity for SNVs
 >  %
Specificity for SNVs
Positive predictive value for SNVs
Clinical sensitivity for structural variants

CPT Codes

81162, 81432, 81433, 81435, 81436, 81479

The CPT codes provided are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Accepted Specimens



Turnaround Time

A report will be issued concurrently with the OncoAlly™ Solid Tumor Analysis report, within 14 days from receipt of required samples.

Contact Us

Please contact customer service to request a kit.

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