CAREERS

Laboratory Supervisor Position

The Laboratory Supervisor Next Generation Sequencing (NGS) is an on-site position in Framingham, MA. The Laboratory Supervisor will be responsible for organizing and directing the daily activities of the genomic diagnostic laboratory and will report to the VP Laboratory Operations and Quality Assurance. The Laboratory Supervisor will be responsible for setting up and implementing technology platforms, sample preparation, for molecular diagnostic applications including but not limited to NGS, and capillary sequencing, supervising laboratory personnel, conducting, and overseeing quality assurance and quality control, and collecting, analyzing, troubleshooting and interpreting laboratory results.

RESPONSIBILITIES

  • Supervise and manage laboratory operations with multiple testing personnel.
  • Plan daily and weekly workload of technicians.
  • Responsible for testing personnel receive regular in-service training and education appropriate for the type and complexity of the laboratory services performed.
  • Establishing and validating technology platforms, and tests.
  • Maintain LIMS, oversee sample accessioning, tracking and storage.
  • Monitor laboratory activities to improve efficiency.
  • Responsible for noting problems and trends, troubleshooting, and problem resolution.
  • Responsible for resolving technical problems and ensuring remedial actions are taken, and documented, whenever test systems deviate from the laboratory’s established performance specifications.
  • Develop and maintain laboratory Standard Operating Procedures.
  • Plan, prepare and supervise laboratory services under regulatory requirements.
  • Maintain and manage laboratory certification and accreditation.
  • Responsible to maintain laboratory records, reports and files
  • Support Manager with laboratory activities and operation.
  • Responsible for ordering and maintaining supplies and reagents.
  • Manage laboratory purchase of inventory, storage and supplies usage.
  • Supervise preparation of samples for capillary sequencing (Sanger) and NGS testing, which will include cell culture, DNA isolation of various sample types, DNA QC, PCR, library preparation library quantification and sequencing on the Illumina, ThermoFisher, PacBio, or Oxford Nanopore sequencing platforms.
  • Assist in assay validation.
  • Interpretation of sequencing quality data.
  • On-time delivery of client sample testing within quality specifications.
  • Adhere to quality management systems and laboratory SOPs.
  • Maintain laboratory in a clean, functional state, as well as cleaning, performing or scheduling equipment and instrument maintenance/calibration/certification, as required

 

EDUCATION

  • BSc, MSc, PhD degree in science or related discipline.

 

KNOWLEDGE AND SKILLS:

  • Working in a regulated environment: BSL2, CLIA laboratory working experience.
  • Sample accessioning, tracking, and storage experience.
  • Processing samples for nucleic acid isolation.
  • Experience with qubit or Pico-green DNA quantification.
  • Experience with library preparation.
  • Experience operating a next generation sequencer (preferred).
  • Experience with nanodrop or bioanalyzer (preferred).
  • Experience with setting up and running laboratory automation equipment (preferred).
  • Excellent organizational skills.
  • Processing of samples which will include nucleic acid isolation of various sample types, PCR, library preparation for Next-Generation Sequencing, and running Next-Generation sequencers.
  • Sample accessioning, tracking, and storage experience.
  • Effective data trending, document control, and technical bench skills.
  • Strong problem-solving, training, team building, and mentoring abilities.
  • Excellent written and verbal communication skills.

 

EXPERIENCE

Minimum two years of experience in a molecular biology laboratory with supervisory experience preferred.

NGS Laboratory Technician/Technologist

The Laboratory Technician or Technologist is an on-site full-time position in Framingham, MA. The Laboratory Technician/Technologist performs testing of clinical DNA specimens for the purpose of diagnosing genetic disease using manual and automated methods, and following established policies and procedures in a professional manner.

RESPONSIBILITIES

  • Adhere to the standard operating procedures (SOPs)
  • Sample accessioning
  • Using LIMS
  • DNA extractions
  • Preparing DNA libraries for next generation sequencing (NGS)Operating liquid handlers
  • Performing sequencing runs on Illumina and other NGS sequencing platforms
  • Conducts diligent record-keeping and reporting
  • Adheres to quality control policies including equipment maintenance, reagent preparation and testing, and general lab practices
  • Assisting with laboratory inventory
  • Meets or exceeds target workload with accuracy
  • Other related duties as assigned

 

QUALIFICATIONS

  • BSc degree in Biology, Medical Technology, or related life science
  • 1-year relevant work experience required for Technologists.
  • Professional verbal and written communication skills

Clinical Product Manager

Are you passionate about developing products that make a real difference in people’s lives? Does the idea of helping patients and their families arrive at a diagnosis sooner excite you? We’re looking for a Product Manager with knowledge of the genetic testing market to join our marketing team. In this role you will work with a cross-functional team to execute the roadmap for expansion of our Genomic Unity® line of whole genome sequencing (WGS)-based tests and to bring those tests to market.

 

RESPONSIBILITIES

  • Manage the full lifecycle of genomic testing products from concept to launch and maintenance
  • Perform product research, market research and competitive analysis to understand testing needs and opportunities
  • Work with clinical and reimbursement experts to define individual test requirements to ensure that both clinical utility and reimbursement standards are met
  • Develop, own and oversee execution of the test launch plan working closely with colleagues in development, clinical, reimbursement and marketing departments to ensure successful completion 
  • Develop positioning and messaging for technical marketing materials and sales enablement
  • Educate sales team on test offerings

 

QUALIFICATIONS

  • An advanced degree (MS, PhD) in a scientific discipline, particularly in genetics / genetic counseling / molecular biology
  • 2+ years product or project management experience in a clinical or life sciences setting

 

REQUIREMENTS

  • Strong analytical and critical thinking skills
  • Self-motivated team player who will roll up their sleeves to get critical work done
  • Able to manage and lead a team of colleagues to complete projects without direct authority
  • Excellent written and verbal communication skills
  • Strong organizational skills and attention to detail

 

LOCATION

Boston, MA metropolitan area preferred, but remote candidates with the right qualifications will also be considered

Content Marketing Manager

Are you passionate about helping people learn about new technologies through writing? Do you enjoy distilling complex scientific concepts into language that the average person understands and finds engaging? Do you like interacting with people through different channels of communication? We’re looking for a Content Marketing Manager with proven creative and technical writing skills to join our marketing team. In this role you will be accountable for developing technical, scientific content that raises brand awareness, drives lead generation and builds customer engagement and retention for our genetic testing products. You will create original content, distributing it via print and digital channels that you manage including the website, social media channels, email and newsletters.

 

RESPONSIBILITIES

  • Create and manage an editorial content calendar that aligns with business goals
  • Create, edit and publish content for brochures and flyers, case studies, presentations, the website, social media campaigns, ad campaigns, blog posts, company newsletters, email campaigns and targeted mail campaigns
  • Channel management of digital content including the website, social channels, email and newsletter distribution
  • Track, analyze and report on content engagement to inform planning for future projects and activities

 

QUALIFICATIONS

  • An advanced degree (MS, PhD) in a scientific discipline, particularly in genetics / molecular biology
  • 2+ years experience writing in a clinical or life sciences setting
  • Must be able to provide writing samples

 

REQUIREMENTS

  • Excellent copy writing skills
  • Proven ability to produce creative, scientifically sound content
  • Self-motivated to proactively reach out and establish dialogue with technical experts who can provide input on relevant topics
  • Strong organizational skills and attention to detail
  • Experience with WordPress and Google Analytics and basic SEO understanding would be beneficial

 

LOCATION

Boston, MA metropolitan area preferred, but remote candidates with the right qualifications will also be considered

Clinical Variant Scientist

As a full-time or part-time, onsite or remote Clinical Variant Scientist located in the US or Israel, you will be responsible for the interpretation and analysis of genetic variants that are identified by our Genomic Intelligence® platform.

RESPONSIBILITIES

Your duties will include interpreting sequence variants in the context of genetic disorders, literature curation, and compiling clinical draft reports. In order to perform your duties, you will be required to:

  • Process and classify variants in accordance with company SOPs
  • Track the variant-scoring process
  • Communicate with customers and peers within the company
  • Consult with the Laboratory Directors, Genetic Counselors or Technical team members regarding variant assessment 
  • Provide feedback for product enhancement

 

TESTING PERSONNEL

A person competent to record and report test results promptly, accurately, and proficiently, and for assuring compliance with applicable regulations. 

QUALIFICATIONS

PhD in Molecular Biology or Genetics or MSc/MS in Genetic Counseling or BS/BSc in a relevant field and 2 years of experience in variant analysis/interpretation

REQUIREMENTS

  • At least 2 years’ experience working in a clinical diagnostic genetic lab using NGS technology and ACMG variant curation
  • Experience with NGS analysis is required

 

LOCATION

Framingham, MA

Adjuvant Sales Representative

RESPONSIBILITIES

  • Source new sales opportunities within geographies across that US that are not
    currently being covered by a Variantyx Sales Rep
  • Utilize follow-up regarding previous ordering clients, inbound leads, outbound
    cold calls and emails
  • Understand customer needs and requirements
  • Enter the qualified opportunities into Salesforce identifying the appropriate Sales
    Rep
  • Close sales and achieve annual goals
  • Research accounts, identify key targets: Geneticists, Genetic Counselors,
    Neurologists, Cardiologists, Oncologists, Maternal Fetal Medicine
  •  Maintain and expand education and utilization of Variantyx testing and
    maintaining a database of prospects within various territories: NH, VT, RI, WI, MI, LA, AL, AR, MS, OK, NM, MT, ID and Southern California. This list if fluid as needs arise.
  • Team with the Clinical Coordinators to build an ordering pipeline
  • Team with the Clinical Science Liaisons to educate key targets

REQUIREMENTS

  • Proven track record of successful genomic testing sales
  • Track record of over-achieving goals
  • Strong knowledge of genomic testing and how it is used in the clinical setting
  • Proficient with Salesforce and web presentation tools
  • Excellent verbal and written communications skills
  • Strong listening, presentation and follow-up skills
  • Ability to multi-task, prioritize, and manage time effectively

 

LOCATION

This position can reside anywhere in the United States.

Medical/Clinical Genetic Review Specialist - Managed Care

In this high visibility role reporting directly to the Associate Medical Director, Managed Care, as the Medical/ Clinical Genetic Review Specialist you will contribute to overall company growth leveraging your medical and clinical genomics expertise to increase patient and physician access to genomic testing and support payer reimbursement of Variantyx testing.

 

RESPONSIBILITIES

  • Contribute to the order medical/ clinical genetics review (triage) process to align medical necessity of test ordered to patient clinical details to ensure patient access by securing payer approval and reimbursement:
    • Review patient medical records/ clinical notes to understand and define the specific clinical scenario to determine the medical necessity of ordered testing
    • Help align test order with medical necessity criteria determined from payer medical coverage and reimbursement policies, and evidence-based medicine from peer-reviewed literature/ clinical guidelines
    • Recommend alternate testing approaches for test orders that align with payer coverage and reimbursement policies.
    • Support pre-authorization and claim submissions, and denial appeals by developing evidence-based rationale to support medical necessity of genomic testing and communicating the value of Variantyx tests to payers
    • Contribute to developing impactful customized letters of medical necessity and denial appeal, articulating the clinical value of Variantyx testing to payers
    • Contribute as necessary to developing dossiers communicating the value of Variantyx testing to various stakeholder segments
    • Maintain ongoing timeliness and throughput of quality deliverables and contribute to improving process efficiency
  • Engage with ordering physicians and their office staff as necessary
  • Help manage and train junior team members as necessary
  • Assist in managing external vendors and consultants relevant to outlined responsibilities
  • Willingness to learn and desire to grow in the role to become an internal expert in the company

QUALIFICATIONS

  • Degree in Genetic Counseling, MD and/or PhD in human genetics, molecular biology, or equivalent experience
  • Experience in medical review and/or utilization management, and/or direct hands-on experience developing letters of medical necessity to support payer reimbursement preferred
  • Experience in HIPAA-regulated work environments
  • Experience and working knowledge of the following:
    • Clinical genetic/ genomic/ next generation sequencing-based testing, including whole exome and whole genome analyses
    • Rare inherited diseases, neurology, metabolic, maternal fetal medicine, and/or cancer
    • Available data sources for medical/ clinical and genomic information, literature review, (e.g., PubMed, GeneReviews, OMIM, ClinVar)
  • Experience, familiarity, and/or willingness to quickly learn in the position the following as relevant to Variantyx genomic testing:
    • Reimbursement environment and mechanisms for genomic/ molecular pathology testing in the US including for commercial, Medicare, and Medicaid insurance segments
    • How to locate, review and interpret US payer medical policies
    • Reimbursement coding including CPT, ICD-10, etc
    • Working with healthcare utilization and health economic data to underscore the burden of disease (e.g., CMS data, AHRQ HCUPnet data)
  • Experience working in a cross-functional team environment, managing one or more direct reports, and/or project consultants

 

REQUIREMENTS

  • Full-time position
  • Excellent written and verbal communication skills with ability to adapt between technical and layperson communication
  • Excellent organizational, time management skills, and ability to multitask and prioritize work
  • Outstanding external and internal customer service orientation
  • Attention to detail and problem-solving skills
  • Strong organizational and interpersonal skills
  • Ability to engage with insurance payer medical representatives (primarily by phone) and maintain relationships as necessary
  • Ability to work independently and as part of a broader team
  • Business travel as needed (expected to be minimal)

 

LOCATION

Framingham, MA or remote-based with travel to the Framingham office as needed

Senior Software Engineer/Tech Lead

For the last 7 years Variantyx has established itself as the industry leader in germline genetic diagnostics all while maintaining agility by keeping the team small. We were the first to launch a comprehensive clinically validated whole genome test including structural variation, short tandem repeats, large chromosomal abnormalities, etc. Innovation and leadership are in our DNA. As we continue to develop and improve our germline solution, Variantyx has set its eyes to the oncology space. To facilitate an easier transition, Variantyx has licensed an industry proven somatic diagnostic tool. As part of the migration, we are in need of a core developer instrumental in helping Variantyx burst into the somatic industry with the same level of leadership and ingenuity as our germline product. Clichés aside, this is an opportunity to actually make an impact both professionally and globally.

In this demanding role, you will be a core member responsible for the rebuild and launch of a new product. In addition, your efforts will help guide cancer patients towards treatments and drugs with the highest likelihood of success. Knowledge of biology or bioinformatics is not required.

 

RESPONSIBILITIES

  • Rebuild and restructure an existing Java-based full-stack product
    • Replace the infrastructure of the product to use open-source alternatives (e.g., DB2 to PostgreSQL, java to typescript/node.js, etc.)
    • Take part in redesigning the system architecture to better suit Variantyx’s needs. This may include different languages, platforms, and/or tools.
  • Develop high quality and efficient code to help support the growth of the product
  • Capable of taking ownership of part or the whole system
  • Work with best-practice development workflows (GitHub, test driven development, etc.)

     

QUALIFICATIONS:

  • B.S. and/or M.S. in computer science (must have already graduated)
  • At least 2 years out-of-university work experience in a software developer position

REQUIREMENTS

  • Strong full-stack engineer 
  • Preferred Languages and tools: Java, Node.js, TypeScript, Angular, Python, PostgreSQL, MongoDB
  • Preferred experience with designing or working with distributed architectures
  • Permanent Resident / Authorized to work in the US

 

LOCATION

Framingham, MA (remote work friendly)

Assistant Quality Assurance (QA)

Variantyx provides genetic testing and manages a complex and highly detailed bioinformatics manufacturing system. We are searching for a creative, energetic individual to join our team as an Assistant Quality Assurance, supporting our quality management program. This role will report to the VP of Lab Operations and Quality Assurance.

About the Position
The Assistant QA will work with other staff to ensure policies, procedures and products adhere to established quality standards and maintain regulatory compliance. The Assistant QA will be highly involved in the preparation and completion of external and internal quality audits and risk assessments. The Assistant QA will provide support in activities such as but not be limited to event management, document and records management, audit management, licensure and accreditation, and sample management. The Assistant QA will also participate in and support company continuous improvement activities.

 

RESPONSIBILITIES

  • Manage and update tracking databases for various processes and quality indicators.
  • Assist in QA of sample management in collaboration across company teams.
  • Create analytical reports of quality indicators. 
  • Document nonconforming events (NCEs) and support staff.
  • Document Corrective and Preventive Actions (CAPAs) and support staff.
  • Assist in monitoring CAPAs to ensure closure and verification of effectiveness.
  • Write, maintain, and update Policies and Procedures across company processes.
  • Assist in the periodic internal and external audits and inspections.
  • Assist in the preparation of audit reports and inspection observations.
  • Assist with compilation of audit findings.
  • Maintain current and accurate quality management records.
  • Support, maintain and continually improve Quality System.

QUALIFICATIONS

  • Bachelor’s Degree and 2+ years in Quality Assurance.
  • Scientific background in molecular biology and/or NGS an advantage.
  • Analytical thinking with superb attention to detail.
  • Excellent oral and written communication skills.
  • Experience or familiarity with diagnostics or clinical lab operations an advantage.
  • Familiarity with QA activities across multiple quality system (e.g., HIPAA, CLIA/CAP). 
  • Ability to work well under pressure while maintaining a professional demeanor.
  • Excellent interpersonal skills.
  • Excellent computer skills.
  • Must be able to organize and handle multiple tasks.
  • Must be a self-starter with a high level of initiative.

 

LOCATION

Framingham, MA or remote-based with travel to the Framingham office as needed.

Clinical Coordinator position

RESPONSIBILITIES

  • Manage administrative intake of cases.
  • Work with hospitals, clinics, facilities and the clinical team to manage requests for services from providers
  • Collect and record medical information
  • Review medico-legal forms
  • Work with insurance companies on prior authorization process
  • Process incoming prior authorizations, including intake, notification and census roles
  • Handle resolution/inquiries from members and/or providers
  • Manage product kits (assembly, shipping and receiving to and from clinicians and patients)

 

REQUIREMENTS

  • Full-time position
  • Fluent in Spanish – Advantage
  • Excellent time management skills and ability to multitask and prioritize work
  • Outstanding customer service orientation
  • Attention to detail and problem-solving skills
  • Excellent written and verbal communication skills
  • Strong organizational and interpersonal skills
  • Ability to manage and maintain relationships with various Insurance payers
  • Responsible care and management of confidential information
  • College degree preferably in life sciences
  • Demonstrated knowledge of office systems, technology and relevant software applications (MS Office Suite)
  • Ability to work independently and as part of a team.

 

LOCATION

Framingham, MA 

Open positions

To apply, please send your cover letter and resume to our Human Resources team at humanresources@variantyx.com.

Apply Today

Please do not submit Protected Health Information (PHI) through this email address.

If you need to submit Protected Health Information (PHI), please call us at 617-209-2090 and we will work with you to submit the information through an alternate mechanism.

Otherwise, please continue: