CAREERS

Assay Development Team Lead - NGS Oncology

Variantyx is a genomic diagnostics company that pioneered routine use of Whole Genome Sequencing in rare disease diagnostics. Now we are expanding into the somatic space and looking for talented professionals to join our growing team in Framingham, MA. 

RESPONSIBILITIES

  • Design and optimization of target enrichment for comprehensive NGS tumor profiling
  • Design and optimization of assay protocols and automation for high throughput applications in a clinical setting
  • Build and supervise oncology assay development team
  • Development, establishment and validation of analytical workflows and methods; interpretation and the documentation of data
  • Anticipation of problems that may affect timing or data quality
  • Execute/supervise research and development activities through all phases of product development
  • Implement new programs, tests, methods, instrumentation, and procedures by investigating alternatives; preparing proposals; developing and performing parallel testing; monitoring progress
  • Manage project deliverables to ensure timely project delivery. Set clear product development timelines and prioritize efforts to deliver on commitments.
  • Developing operations, quality, and troubleshooting procedures
  • Full time onsite position based in Framingham, MA 


REQUIREMENTS

  • MS in the Biological Sciences with at least 5 years of experience or PhD in Molecular Biology with at least 3 years of experience developing clinical NGS oncology assays
  • Must have demonstrated experience in end-to-end assay development for NGS somatic cancer solutions
  • Excellent communication skills
  • Strong team player with the ability to work with others 
  • Self-driven and works well in an interdisciplinary team with minimal direction
  • Strong organizational skills


LOCATION

Framingham, MA

NGS Laboratory Technician/Technologist

The Laboratory Technician or Technologist is an on-site full-time position in Framingham, MA. The Laboratory Technician/Technologist performs testing of clinical DNA specimens for the purpose of diagnosing genetic disease using manual and automated methods, and following established policies and procedures in a professional manner.

RESPONSIBILITIES

  • Adhere to the standard operating procedures (SOPs)
  • Sample accessioning
  • Using LIMS
  • DNA extractions
  • Preparing DNA libraries for next generation sequencing (NGS)Operating liquid handlers
  • Performing sequencing runs on Illumina and other NGS sequencing platforms
  • Conducts diligent record-keeping and reporting
  • Adheres to quality control policies including equipment maintenance, reagent preparation and testing, and general lab practices
  • Assisting with laboratory inventory
  • Meets or exceeds target workload with accuracy
  • Other related duties as assigned

 

QUALIFICATIONS

  • BSc degree in Biology, Medical Technology, or related life science
  • 1-year relevant work experience required for Technologists.
  • Professional verbal and written communication skills

Digital Marketing Manager

This individual will develop and drive digital marketing strategies to advance the Variantyx brand name and online presence. In this role, you will take ownership of the creation and development of our digital properties, improving the client experience through data-driven personalization and optimization.

RESPONSIBILITIES

  • Execute measurable digital marketing strategies and tactics driven by company Marketing plans
  • Channel management of digital content including the website, social channels, email and newsletter distribution
  • Track, analyze and report on content engagement to inform planning for future projects and activities
  • Strategize, create and maintain media content including images, gifs, short videos, etc.
  • Manage Hootsuite account – responsible for creation & scheduling of all posts across social channels ( primarily Twitter, LinkedIn, Facebook)
  • Manage Vimeo account
  • Craft plans to increase Search Engine Optimization of Variantyx web ranking
  • Manage promoted/sponsored Ad Programs and Google Adwords
  • Collaborate with external team regarding large out-of-scope website changes
  • Partner with Product Marketing Management team to develop end-to-end digital marketing campaigns
  • Work with Product Owners to design impactful content for website and social media use
  • Monitor key metrics to track marketing ROI
  • Monitor trends and participate in social media conversations relevant to the industry and business
  • Identify and proactively engage with advocacy groups, research organizations, bloggers, news and media producers, etc who can help spread awareness
  • Build and manage a user community, facilitate engagement with and among community members

 

QUALIFICATIONS

  • Bachelor’s degree in one of the following or related disciplines: marketing, business, communications or journalism
  • A focus on media arts is desirable

 

REQUIREMENTS

  • Adobe creative suite experience
  • Salesforce.com (Pardot) experience a plus
  • Data-driven. You have experience working with data, product, and business teams to craft data-driven action plans that align strongly with organizational priorities
  • Strategic thinker. Proven ability to identify strategic opportunities, set aggressive objectives, and drive key business priorities
  • Highly consistent and organized. Proven ability to manage multiple projects/tasks concurrently under aggressive timelines in a dynamic environment
  • Results-oriented. Fluent in CRO, “Conversion Rate Optimization”
  • Proven ability to drive an excellent user acquisition strategy
  • Excellent oral and written communication skills
  • Self-motivated and independent thinker, with aptitude to work autonomously
  • Experience working for healthcare, laboratory services industry or life sciences a plus

Oncology Product Marketing Manager

Are you passionate about developing products that make a real difference in people’s lives? Does the idea of helping patients and their families arrive at a diagnosis sooner excite you? We’re looking for a Product Manager with knowledge of the oncology testing market to join our marketing team. In this role, you will be an internal subject matter expert, working with a cross-functional team to execute the roadmap for expansion of our Genomic Unity® Oncology line of whole genome sequencing (WGS)-based tests and to bring those tests to market. You will also use your product marketing expertise to promote and drive awareness and adoption of the tests within the portfolio.

 

RESPONSIBILITIES

You will be leading product planning and execution throughout the product lifecycle.

  • Monitor, evaluate, and analyze marketing activities of key competitors to identify trends, opportunities, and best practices and to understand the competitive landscape.
  • Perform product research, market research and competitive analysis to understand testing needs and opportunities.
  • Craft compelling content for marketing materials, including print and digital collateral, sales enablement materials, and presentations. Drive positioning/messaging in key channels (email, social media, newsletter, and blog).
  • Create training and educate sales team on test offerings.
  • Collaborate with clinical, development & genetic counseling teams to produce Case Studies and White Papers.
  • Work with clinical and reimbursement experts to define individual test requirements to ensure that both clinical utility and reimbursement standards are met.
  • Develop timelines, coordinate releases, and ensure Go To Customer plans are in place to communicate value to internal and external audiences.
  • Support nationwide Sales Team.
  • Collaborate with Sales and customers to serve as the direct line of communication with end users of your products to maintain a constantly evolving backlog of future enhancements.
  • Perform product maintenance and updates to test requisition forms, report language, physician and patient consent forms.

 

QUALIFICATIONS

  • Life science degree required. An advanced degree in genetics / molecular biology (MS, PhD) would be an advantagee
  • 3+ years product or marketing management experience in a clinical or life sciences setting with at least one year in somatic oncology marketing.

 

REQUIREMENTS

  • Product marketing expertise
  • Strong analytical and critical thinking skills
  • Self-motivated team player who will roll up their sleeves to get critical work done
  • Able to manage and lead a team of colleagues to complete projects without direct authority
  • Excellent written and verbal communication skills
  • Strong organizational skills and attention to detail

Medical/Clinical Genetics Review Manager - Market Access and Reimbursement

Variantyx is a rapidly growing CLIA/CAP laboratory providing highly specialized genetic testing to clinicians and their patients. We have developed a proprietary diagnostic testing platform based on whole genome sequencing (WGS) that detects all major types of genetic changes, thereby reducing the false negative rate of testing, short-circuiting the prolonged diagnostic odyssey for patients with rare diseases and inherited cancers, and reducing the overall cost per diagnosis.

POSITION SUMMARY

In this high visibility role, you will be part of the Market Access and Reimbursement team that reports directly to the Associate Medical Director. This is a growing team of healthcare professionals who have a passion for and expertise in medical genetics and test utilization management. This is an inward-facing role, with no patient or provider contact. However, contact with payers will be an essential part of the position on a case-by-case basis. This position provides you with the opportunity to contribute to overall company growth by leveraging your medical/clinical genetics expertise and understanding of payer medical policies to advocate for patient access to appropriate genomic testing, while optimizing payer acceptance and reimbursement.

RESPONSIBILITIES

  • Contribute to medical/clinical genetics review (“triage”) process to support  medical necessity of ordered testing using patient clinical information and payer coverage and reimbursement policies, ensuring patient access to genomic testing, and obtaining payer approval for coverage and reimbursement.
    • Review patient medical records within the context of ordered testing to optimize and advocate for necessary testing with payers.
    • Determine whether the ordered testing aligns with payer coverage and reimbursement policies by comparing patient’s clinical information with the payer policy and medical necessity criteria.
    • When testing does not align with payer coverage and reimbursement policies as ordered, recommend alternative, clinically appropriate testing strategies based on applicable payer policies, and clinical guidelines and evidence-based medicine from peer-reviewed literature.
    • Support pre-authorizations, claim submissions, and denial appeals by developing strong and succinct evidence-based rationale (letters of medical necessity, letters of appeal, etc.) that communicate the medical necessity of requested tests, and the differentiating value of the specific Variantyx  tests applicable to each case.
    • Maintain ongoing timeliness and throughput of quality deliverables.
  • Willingness and desire to learn and grow in the role to become an internal knowledge expert in the company.

     

QUALIFICATIONS

  • Master’s Degree in Genetic Counseling, and/or MS or PhD in Human Genetics, Molecular Biology, or equivalent experience.
    • For genetic counselor applicants:
      • Master’s Degree from an ACGC accredited program 
      • ABGC board-certified OR board-eligible
      • Active licensure in the state where you live, if applicable
  • Experience in medical review and/or utilization management, and/or hands-on experience in developing letters of medical necessity to support pre-authorization and payer reimbursement preferred.
  • Experience in HIPAA-regulated work environments.
  • Experience and working knowledge of the following:
    • Clinical genetic/genomic/next generation sequencing-based testing, including whole exome and whole genome analyses.
    • Rare inherited diseases, neurology, metabolic, maternal fetal medicine, and/or cancer.
    • Available data sources for medical/clinical genetic and genomic information, and literature review (e.g., PubMed, GeneReviews, OMIM, ClinVar, guideline societies, health technology assessments).
  • Experience, familiarity, and/or willingness to quickly learn the following as relevant to Variantyx genomic testing: 
    • Reimbursement environment and mechanisms for genomic/molecular pathology testing in the US including for commercial, Medicare, and Medicaid insurance segments. 
    • How to locate, review, and interpret US payer medical policies.
    • Reimbursement coding for genomic testing (e.g., CPT, ICD-10-CM).
    • Working with healthcare utilization and health economic data to underscore the burden of disease (e.g., CMS data, AHRQ HCUPnet data).
  • Experience working in a cross-functional team environment including both technical and non-technical colleagues.

REQUIREMENTS OF ROLE 

  • Full-time position.
  • Excellent written and verbal communication skills with ability to adapt between technical and layperson communication.
  • Excellent organizational, time management skills, and ability to multitask and prioritize work.
  • Attention to detail and problem-solving skills.
  • Strong organizational and interpersonal skills.
  • Ability to work independently and as part of a broader team.
  • Business travel as needed (expected to be minimal).

LOCATION

Framingham, MA OR remote-based with travel to the Framingham office as needed. 

Clinical Variant Scientist

As a full-time or part-time, onsite or remote Clinical Variant Scientist located in the US or Israel, you will be responsible for the interpretation and analysis of genetic variants that are identified by our Genomic Intelligence® platform.

RESPONSIBILITIES

Your duties will include interpreting sequence variants in the context of genetic disorders, literature curation, and compiling clinical draft reports. In order to perform your duties, you will be required to:

  • Process and classify variants in accordance with company SOPs
  • Track the variant-scoring process
  • Communicate with customers and peers within the company
  • Consult with the Laboratory Directors, Genetic Counselors or Technical team members regarding variant assessment 
  • Provide feedback for product enhancement

 

TESTING PERSONNEL

A person competent to record and report test results promptly, accurately, and proficiently, and for assuring compliance with applicable regulations. 

QUALIFICATIONS

PhD in Molecular Biology or Genetics or MSc/MS in Genetic Counseling or BS/BSc in a relevant field and 2 years of experience in variant analysis/interpretation

REQUIREMENTS

  • At least 2 years’ experience working in a clinical diagnostic genetic lab using NGS technology and ACMG variant curation
  • Experience with NGS analysis is required

 

LOCATION

Framingham, MA

Reproductive Genetics Product Marketing Manager

Are you passionate about developing products that make a real difference in people’s lives? Does the idea of helping patients and their families arrive at a diagnosis sooner excite you? We’re looking for a Product Manager with knowledge of the oncology testing market to join our marketing team. In this role, you will be an internal subject matter expert, working with a cross-functional team to execute the roadmap for expansion of our Genomic Unity® Women’s Health line of whole genome sequencing (WGS)-based tests and to bring those tests to market. You will also use your product marketing expertise to promote and drive awareness and adoption of the tests within the portfolio.

RESPONSIBILITIES

You will be leading product planning and execution throughout the product lifecycle.

  • Monitor, evaluate, and analyze marketing activities of key competitors to identify trends, opportunities, and best practices and to understand the competitive landscape.
  • Perform product research, market research and competitive analysis to understand testing needs and opportunities.
  • Craft compelling content for marketing materials, including print and digital collateral, sales enablement materials, and presentations. Drive positioning/messaging in key channels (email, social media, newsletter, and blog).
  • Create training and educate sales team on test offerings.
  • Collaborate with clinical, development & genetic counseling teams to produce Case Studies and White Papers.
  • Work with clinical and reimbursement experts to define individual test requirements to ensure that both clinical utility and reimbursement standards are met.
  • Develop timelines, coordinate releases, and ensure Go To Customer plans are in place to communicate value to internal and external audiences.
    Support nationwide Sales Team.
  • Collaborate with Sales and customers to serve as the direct line of communication with end users of your products to maintain a constantly evolving backlog of future enhancements.
  • Perform product maintenance and updates to test requisition forms, report language, physician and patient consent forms.

 

QUALIFICATIONS

  • Life science degree required. An advanced degree in genetics / molecular biology (MS, PhD) would be an advantage.
  • 3+ years product or marketing management experience in a clinical or life sciences setting with at least one year in maternal fetal health prenatal marketing.

 

REQUIREMENTS

  • Product marketing expertise
  • Strong analytical and critical thinking skills
  • Self-motivated team player who will roll up their sleeves to get critical work done
  • Able to manage and lead a team of colleagues to complete projects without direct authority
  • Excellent written and verbal communication skills
  • Strong organizational skills and attention to detail

Office administrator / Customer support

We are looking to add energetic, outgoing and caring office administrators to help with supporting customers and employees with daily activities and tasks.

 

RESPONSIBILITIES

  • Attend the office daily and ensure presence during working hours. 
  • Receive and route customer calls, assist with resolving issues over time with training
  • Manage incoming and outgoing mail, FedEx and UPS
  • Assembly, recording and timely delivery of sample collection kits
  • Periodic review of orders and invoices 
  • Stock, inventory and orders management
  • Task management, collaboration and assistance to Clinical Coordinators and sales

 

QUALIFICATIONS

  • Courteous, caring and always willing to assist others
  • Dependable, detail oriented with a sense of urgency
  • Willing to learn and internalize procedures and methods

 

REQUIREMENTS

  • Computer skills including web surfing 
  • Use of Microsoft office or Google equivalent tools
  • Multitasking
  • Collaborating and working with others

 

LOCATION

Framingham, MA 

Genetics Marketing Specialist

Are you passionate about marketing products that make a real difference in people’s lives? Does the idea of helping patients and their families arrive at a diagnosis sooner excite you? We’re looking for a Genetics Marketing Specialist with deep knowledge of the genetic testing market to join our team. In this role, you will work closely with our Product Marketing Team to develop meaningful marketing messaging for multiple product lines within the Variatnyx portfolio. 

 

RESPONSIBILITIES

Your primary role will be to develop content that supports the Variantyx portfolio of whole genome sequencing based genetic testing products. Your responsibilities will include the ideation and execution of new and innovative content for: social media channels, website, blogs, videos, newsletters, flyers and other creative assets, as well as ongoing monitoring and maintenance of marketing collateral.

  • Work with Product Marketing Team to craft compelling content for marketing materials, including print and digital collateral, sales enablement materials, and presentations
  • Maintain thorough knowledge of assigned products. Identify appropriate sources of relevant data, interpret, evaluate and incorporate information from various sources
  • Work with clinical teams to produce data-driven stories rooted in clinical insights 
  • Develop presentations and talking points for nationwide sales team 
  • Collaborates closely with product marketing team and clinical consultant team members to identify and share stories and use cases via case studies, blogs, and/or white papers
  • Iteratively test and evaluate campaigns and strategies to drive awareness, acquisition and engagement metrics
  • Create a marketing performance measurement platform to evaluate program effectiveness
  • Support the development and active maintenance of marketing assets, a content management system 
  • Manage the creative process for multiple projects, end-to-end, in a rapid and efficient manner
  • Draft abstracts for speaking opportunities and events

QUALIFICATIONS:

  • Life science degree required. An advanced degree in genetics / molecular biology (MS, PhD) would be an advantage
  • 3+ years product or marketing management experience in a clinical or life sciences setting
  • Ability to work efficiently and independently, thrive in a fast-paced environment, and juggle multiple projects/reprioritize work as needed

REQUIREMENTS

  • Demonstrated ability to write clinical content for healthcare marketing programs. 
  • Excellent written and verbal communication skills
  • Self-motivated team player who will roll up their sleeves to get critical work done
  • Collaborative drive for shared success, seamless project management, and a desire to jump in to help get things done
  • Strong analytical and critical thinking skills
  • Strong organizational skills and attention to detail 

 

LOCATION

Remote work friendly

Bioinformatics Engineer

For the last 7 years Variantyx has established itself as the industry leader in germline genetic diagnostics all while maintaining agility by keeping the team small. We were the first to launch a comprehensive clinically validated whole genome test including structural variation, short tandem repeats, large chromosomal abnormalities, etc. Innovation and leadership is in our DNA. As we continue to develop and improve our germline solution, Variantyx has set its eyes to the oncology space. To facilitate an easier transition Variantyx has licensed an industry proven somatic diagnostic tool. As part of the migration, we are in need of a bioinformatician instrumental in helping Variantyx burst into the somatic industry with the same level of leadership and ingenuity as our germline product. Cliches aside, this is an opportunity to actually make an impact both professionally and globally.

In this demanding role, you will be a core member responsible for developing a somatic pipeline. 

 

RESPONSIBILITIES

  • Develop a tumor-only somatic pipeline capable of calling small sequence changes, indels, structural variants, gene fusions, etc.
  • Validate the pipeline using known truth-sets
  • Develop high quality and efficient code
  • Capable of taking ownership of part or the whole system


QUALIFICATIONS

  • B.S. and/or M.S. in computer science, bioinformatics or a related field (must have already graduated)
  • At least 5 years out-of-university work experience in a bioinformatics position
  • Permanent Resident / Authorized to work in the US

REQUIREMENTS:

  • Preferred Languages and dbs: Python, PostgreSQL, MongoDB
  • Hands on experience working with NGS datasets
  • Strong experience and familiarity with standard bioinformatics tools, e.g. bwa, samtools, bedtools, gatk/mutec, etc.
  • Experience working with mutation and/or gene curation sources such as ClinVar, HGMD, OMIM, etc. 
  • Preferred experience with designing or working with distributed architectures


LOCATION

Framingham – MA (remote work friendly)

IT Service Desk Technician

Join our small but mighty IT team here at Variantyx as an IT Service Desk Technician to support our workforce as we scale in the coming years. 

You will be providing phenomenal end-user IT support for our growing global workforce. You will be aiding the team with our ongoing IT projects through implementation, technical documentation, and training our end users on the new tech. You’ll have the opportunity to bring forward new hardware and software solutions to improve our customers’ interactions with the IT environment. Gain first-hand experience with a cloud-based modern IT environment. Help manage our end-user equipment life cycle and training staff on correct operating procedures. 

RESPONSIBILITIES

  • Direct point of contact for employee IT support requests
  • Manages IT help request ticket queue
  • Ensures timely completion, follow-up, and documentation of all support requests
  • Diagnosing and resolving hardware/software problems
  • New employee onboarding, including setup and employee IT orientation
  • Improving our IT environment by developing business processes/procedures by researching and identifying enabling systems/technologies
  • Document and maintain IT procedures
  • Supporting Mac and Windows machines hardware and software configurations.
  • Administration of Google Workspace and AzureAD
  • Administration of Mosyle and Microsoft Intune
  • Troubleshooting network issues
  • Training staff on newly installed hardware and software systems.
  • Fixing hardware, software, and networking issues.
  • Ensuring security software is kept up to date.
  • May require occasional work outside of regular business hours

 

QUALIFICATIONS

  • 1-3 years IT support experience in a Windows/Mac environment
  • Some experience with Google Workspace
  • The ability to multitask and manage time with limited supervision is a must
  • Strong communication skills via email/ in person
  • Additional requisites include: strong organizational and interpersonal skills, a process-oriented mindset, strong problem solving and analytical skills, the ability to work independently, a results-oriented attitude with the ability to prioritize, and a talent for interacting with people at all levels
  • Strong customer service skills
  • Must be available to work within the office at least two days a week. 


BONUS QUALIFICATIONS

  • 2 or 4-year degree in Computer Science or Information Systems
  • Scripting and automation background 
  • IT Certifications (A+, Network+)


LOCATION

Framingham, MA 

Clinical Coordinator position

RESPONSIBILITIES

  • Manage administrative intake of cases.
  • Work with hospitals, clinics, facilities and the clinical team to manage requests for services from providers
  • Collect and record medical information
  • Review medico-legal forms
  • Work with insurance companies on prior authorization process
  • Process incoming prior authorizations, including intake, notification and census roles
  • Handle resolution/inquiries from members and/or providers
  • Manage product kits (assembly, shipping and receiving to and from clinicians and patients)

 

REQUIREMENTS

  • Full-time position
  • Fluent in Spanish – Advantage
  • Excellent time management skills and ability to multitask and prioritize work
  • Outstanding customer service orientation
  • Attention to detail and problem-solving skills
  • Excellent written and verbal communication skills
  • Strong organizational and interpersonal skills
  • Ability to manage and maintain relationships with various Insurance payers
  • Responsible care and management of confidential information
  • College degree preferably in life sciences
  • Demonstrated knowledge of office systems, technology and relevant software applications (MS Office Suite)
  • Ability to work independently and as part of a team.

 

LOCATION

Framingham, MA 

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