Identify the Cause of Charcot-Marie-Tooth Symptoms

One test, clear answers.

Genomic Unity® provides the most comprehensive genetic testing available.

Learn about CMT testing today

What is Charcot-Marie-Tooth?

Charcot-Marie-Tooth (CMT) is a nerve disorder within the neuropathy family characterized by progressive loss of muscle strength in the hands, legs and feet. Common symptoms include:

  • Weakness in lower leg muscles and feet
  • Foot deformities like bent toes or a high arch
  • Tingling, burning, or numbness sensation in hands or feet
  • Loss of temperature sensation in hands or feet
  • Difficulty lifting your foot when walking

Symptoms usually begin in childhood, but can first appear in adulthood.

Why genetic testing is critical

While CMT is often caused by changes in the number of copies of the PMP22 gene, DNA changes in >100 different genes can be responsible.

Genetic testing is essential to rule out related neuropathies, confirm a diagnosis, and guide treatment. Early genetic testing may:

  • Inform prognosis
  • Identify targeted treatments or clinical trials
  • Guide family planning decisions

Genomic Unity® provides the most comprehensive testing

When it comes to genetic testing, technology matters.

Traditional testing often involves sequential tests that may miss crucial information. Genomic Unity® uses whole genome sequencing to detect DNA changes ranging in size from single base changes to large structural changes – including changes in the number of PMP22 copies – with a single test.

Our advanced technology ensures the most accurate and complete results available.

Why choose Genomic Unity®?

  • One test replaces multiple sequential tests
  • Get your results in just 4-8 weeks
  • Simple insurance and self-pay options

Ask your doctor about Genomic Unity® testing for CMT

Ask your doctor about Genomic Unity® testing

Talking with your healthcare provider is the first step. Start a conversation using these questions:

  • What type of genetic test is best for my symptoms?
  • What genetic conditions can the test detect or miss?
  • How accurate are the results?

FAQs

    • Genomic Unity® is recommended if your healthcare provider suspects CMT or another nerve disorder.

    • Genomic Unity® detects CMT in addition to related nerve disorders including:

      • Giant axonal neuropathy
      • Hereditary distal motor neuropathy with myopathic features (HMNMYO)
      • Hereditary neuropathy with liability to pressure palsies (HNPP)

    • A test report is sent to your doctor within 4-8 weeks of receiving your sample.

    • Yes! Genomic Unity® is covered by most insurances. For cases where insurance coverage is not available, we offer self pay pricing.

    • Genomic Unity® testing must be ordered by a healthcare provider.

      If your healthcare provider needs assistance with obtaining test order forms, sample collection kits, etc, please contact us – we’re happy to help.

Ready to learn more?

Connect with a Clinical Coordinator to discuss Genomic Unity® testing. We’re here to help you understand your options.

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