When a loved one has seizures, genetic answers matter

One test, clear answers.

Genomic Unity® provides the most comprehensive epilepsy testing available.

What is epilepsy?

Epilepsy is a neurological condition characterized by recurrent, unprovoked seizures. It affects people of all ages and can result from a wide range of causes, including genetic factors.

Genetic forms of epilepsy often appear early in life and may additionally be associated with:

Developmental delays
Intellectual disability
Other neurological symptoms

Why genetic testing is critical

Epilepsy can be caused by DNA changes in hundreds of different genes – including some with complex changes known as repeat expansions.

Genetic testing is essential to ruling specific genetic causes in or out. Early genetic testing may:

Inform prognosis
Guide treatment decisions, including eligibility for targeted therapies
Shape family planning decisions

Genomic Unity^® provides the most comprehensive testing

When it comes to genetic testing, technology matters.

Traditional testing often involves sequential tests that can leave diagnostic gaps. Genomic Unity^® uses whole genome sequencing to detect all variant types associated with epilepsy. It detects DNA changes ranging in size from single base changes to large structural changes – including repeat expansions in 6 epilepsy genes – with a single test.

Our advanced technology ensures the most accurate and complete results available.

Why choose Genomic Unity^®?

One test replaces multiple sequential tests
Covers 6 epilepsy repeat expansion genes*
Get your results in just 4 weeks
Simple insurance and self-pay options

*Includes AFF2, ARX, CSTB, DIP2B, FMR1, and GLS.

Ask your doctor about Genomic Unity^® testing for epilepsy

How to talk with your provider about epilepsy genetic testing

If you or a loved one has epilepsy, ask your provider about comprehensive genome testing. You can share:

Variantyx Genomic Unity® analyzes the entire genome, detecting variant types missed by CMA, panels, and exome sequencing
Variantyx expert analysis reduces variants of uncertain significance
Detailed clinical reports clearly explain findings
One comprehensive test can replace multiple rounds of testing
Variantyx facilitates access to genetic counseling support

Patient Success Stories

Three children, three long diagnostic journeys – Answers found for each with a single test

We have thoroughly enjoyed teaming with Variantyx in Jansen’s genetic odyssey. We are forever grateful to Variantyx for uncovering our daughter’s genetic mutation that was considered to be undiscoverable for years.

Suzanne & Brent Jones | Parents of Jansen Jones

Jansen’s story

10-year-old girl

FRA12A intellectual disability

This patient had epilepsy and global developmental delays, plus fatigue and headaches that made attending a full day of school impossible. She had already undergone exome testing with negative results.

Variantyx Genomic Unity® testing identified a pathogenic repeat expansion in the DIP2B gene, finally providing a diagnosis. The result explained her symptoms, plus the symptoms of a close maternal relative.

Learn more

2-year-old boy

CDKL5-deficiency disorder

This patient experienced seizures and developmental delays. CMA, epilepsy panels, and exome sequencing had all been negative.

Comprehensive genome analysis from Variantyx detected a single exon deletion in CDKL5, leading to a diagnosis of CDKL5-deficiency disorder. This diagnosis made him eligible for ganaxolone, a targeted therapy for CDKL5-related epilepsy, providing the opportunity for more personalized treatment.