clinician treating a patient

Revolutionizing genetic testing for rare disease patients

While traditional tests detect only certain types of changes in an individual's DNA, whole genome testing has the ability to detect nearly all known and potential disease-causing changes with a single test. It provides the most comprehensive testing option for patients currently stuck in a diagnostic odyssey. As well as for patients who are new to genetic testing.

Genomic Unity™ is like an exome test, but better. It uses WGS technology to produce more comprehensive exome data, plus additional data that a regular exome test can't provide.

The advantages of whole genome testing


Better coverage of exonic variants

Because the entire genome is sequenced without relying on PCR amplification, WGS produces a consistent read depth. This dramatically reduces the number of low coverage areas that can lead to missed exonic variant calls in other types of testing.

additional variants

Detection of additional variant types

WGS’s consistent read depth makes it possible to detect small sequence changes, structural variants, tandem repeat expansions and mitochondrial variants all within a single assay. Including known disease-causing variants in non-coding regions.

rerun analysis

Ability to rerun analyses, without resequencing

Because the DNA regions of interest are not predetermined, WGS data can be stored and reanalyzed at any time. Without collecting another sample, performing another sequencing run or undertaking another genetic test.

Variants detected and analyzed by Genomic Unity™

SNVs checkmark
Small indels (<50bp) checkmark
Structural variants (≥50bp):





Mitochondrial variants (≥4% heteroplasmy) checkmark
Tandem repeat expansions checkmark

deeper dive

Take a deeper dive into the data

Performance statistics

Read the BMC Genomics article that documents the clinical validation of our structural variant pipeline

Variantyx reports on variants related to the reason(s) for testing. In some instances, such as when a phenotype-relevant variant or gene is associated with multiple disorders, incidental findings may be identified and reported. In addition to phenotype-driven analysis, patients may opt-in to receive pathogenic and likely pathogenic findings in the set of 59 medically actionable genes recommended by the American College of Medical Genetics (ACMG) for secondary/incidental findings.

Suspected diagnoses compatible with testing


Brain malformations


Congenital heart defects and cardiomyopathies


Epilepsy disorders


Mitochondrial disorders


Motor neuron disorders


Movement disorders


Neurodegenerative disorders


Neurodevelopmental disorders


Neuromuscular disorders




Ophthalmology and hearing loss disorders


Skeletal and connective tissue disorders

We make the genetic testing process as easy as possible


Flexible billing

We accept insurance, institutional and direct patient pay, performing all benefits investigation in-house

Review payment options


Fast turnaround

Receive a clinical report signed by our board-certified clinical geneticists within ~8 weeks of sample receipt

View sample requirements


Timely support

Our clinical coordinators and geneticists are always available to answer questions - how can we help?

Request an appointment

How to order testing

1. Complete the required form, with billing information
Genomic Unity™ test requisition and consent form
2. Collect the sample
3. Mail the sample via USPS
4. Receive the report


Request a sample kit


View additional resources


Request a sample kit

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