Variantyx Wellness™ Test

Helping your patients take charge of their health

The health of your patients and their families is important to you, and to them. Variantyx Wellness™ is a genetic screening test that provides a powerful tool to help you and your patients identify predisposing health risks encoded in their DNA. Risks that may have the potential to affect their future health, or the health of their children. Risks that once made aware, it may be possible to delay, diminish or avoid the effects of through lifestyle or preventative healthcare changes, or through identifying problems as early as possible with timely screening. Variantyx Wellness™ delivers the knowledge you need to provide the best preventative care possible.

Advanced technology identifies more variants

Many genetic tests use sequencing technologies which look at only a small fraction of our DNA. Exomes cover 2% of our DNA while targeted gene panels cover less than 0.02% and SNP arrays cover less than 0.01%. In contrast, Variantyx Wellness™ uses whole genome sequencing (WGS) which looks at our entire DNA. While this is very important, complete DNA sequencing alone isn’t enough. Variantyx Wellness™ additionally pairs WGS with proprietary data analysis algorithms that detect more different types of variants (DNA changes that cause disease or increase the risk of developing a disease) than any other WGS-based test. The result is a highly sensitive genetic test that identifies hard to detect variants like the pathogenic BRCA1 ex9-12del variant that occurs in >10% of breast cancer patients of some ethnicities. Or like FMR1 premutation repeat expansion alleles which 1 in 178 women silently carry. Detection of these types of mutations often requires independent, targeted testing, but Variantyx Wellness™includes them, and many others, within a single test. While a negative genetic test result can never completely rule out the possibility of an undetected pathogenic variant, Variantyx Wellness™ provides greater confidence that all relevant variants have been screened.

Screen for thousands of conditions with a single test

By looking at the patient’s entire DNA, Variantyx Wellness™ screens for predisposition to an unlimited number of conditions with a single test. Variantyx Wellness™ looks for variants that can increase an individual’s lifetime risk of developing cancer. It also looks for variants that can affect heart health, predispose an individual to diabetes or autoimmune disease, lead to early onset Alzheimer’s disease and much more. For patients of childbearing age, Variantyx Wellness™ screens for silent carrier mutations known to be responsible for approximately 5,000 rare inherited disorders described in the scientific literature. In addition, Variantyx Wellness™ screens for pharmacogenomic variants that influence how well an individual responds to different drugs, helping guide the choice of medication or dosage while protecting patients from adverse reactions or ineffective treatment.

As our scientific knowledge grows, patient data is reanalyzed

New information about variants and genes associated with disease becomes available every day. Similarly, data analysis algorithms continue to evolve and improve. This is why Variantyx Wellness™ includes the option to reanalyze your patient’s data in the second and fourth year following the original analysis. Without collecting a new sample, performing new sequencing or charging extra fees.

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