Ask Your Healthcare Provider About IriSight™ Prenatal Testing
Your baby’s DNA tells a story. A story of their future health. With IriSight™ prenatal testing, we see more of their story.
What you need to know
Genetic testing looks for DNA changes that can affect the health of your baby. During pregnancy there are many types of genetic testing to consider. Oftentimes the testing journey begins with carrier screening and/or NIPT (noninvasive prenatal testing, also referred to as NIPS or noninvasive prenatal screening).
One doesn’t test your baby directly and the other is a predictive test.
Carrier screening identifies DNA changes that you or your baby’s father could pass on, while NIPT predicts whether your baby has a high or low risk of having a certain chromosomal condition. When a definitive answer or a more complete picture is desired, diagnostic chromosomal microarray (CMA) and exome or genome testing may be considered.
Whole genome testing reveals more in every test
Different types of genetic testing look at different types of DNA changes. NIPT and CMA are able to detect large chromosomal changes, such as extra copies of chromosome 21 which cause Down syndrome. Most NIPTs limit their analysis to only a subset of chromosomes while CMAs analyze all chromosomes.
Exome and genome testing can additionally detect single base changes, such as changes in the CFTR gene that cause cystic fibrosis.
However, exome and genome testing are not equivalent.
Genome sequencing generates uniform coverage of >98% of your baby’s DNA. In comparison, exome sequencing removes and skews data, generating fragmented coverage of only 1-2% of your baby’s DNA.
By pairing genome sequencing with our Genomic Intelligence® proprietary analytical software, our IriSight™ portfolio provides the most comprehensive testing possible – detecting DNA changes without the size and complexity limitations that are typical of exome testing.
The result is a more complete reading of your baby’s story.
Learn more about different test types and sequencing technologies.
Talk to your doctor or genetic counselor about whether genetic testing is right for you. And if so, which genetic test is the best fit.
IriSight™ testing provides a more comprehensive alternative to NIPT and CMA
IriSight™ CNV Analysis
A diagnostic test that uses whole genome sequencing to detect chromosomal abnormalities.
Starting a conversation with your healthcare provider
Talking with your doctor or a genetic counselor is an important step in the process of making a decision about whether genetic testing is right for you. And if so, which genetic test is the best fit. The following questions may help get the conversation started:
- Based on my family history, personal history and this pregnancy, what types of prenatal genetic testing are available to me? Carrier screening? NIPT? CMA? Exome or genome?
- What types of genetic conditions will each test detect?
- What types of genetic conditions will each test NOT detect?
- What possible results can I expect from each test?
- How accurate is each test?