Bioinformatics Engineer

For the last 7 years Variantyx has established itself as the industry leader in germline genetic diagnostics all while maintaining agility by keeping the team small. We were the first to launch a comprehensive clinically validated whole genome test including structural variation, short tandem repeats, large chromosomal abnormalities, etc. Innovation and leadership is in our DNA. As we continue to develop and improve our germline solution, Variantyx has set its eyes to the oncology space. To facilitate an easier transition Variantyx has licensed an industry proven somatic diagnostic tool. As part of the migration, we are in need of a bioinformatician instrumental in helping Variantyx burst into the somatic industry with the same level of leadership and ingenuity as our germline product. Cliches aside, this is an opportunity to actually make an impact both professionally and globally.

In this demanding role, you will be a core member responsible for developing a somatic pipeline.

Responsibilities

  • Develop a tumor-only somatic pipeline capable of calling small sequence changes, indels, structural variants, gene fusions, etc.
  • Validate the pipeline using known truth-sets
  • Develop high quality and efficient code
  • Capable of taking ownership of part or the whole system

Qualifications

  • B.S. and/or M.S. in computer science, bioinformatics or a related field (must have already graduated)
  • At least 5 years out-of-university work experience in a bioinformatics position
  • Permanent Resident / Authorized to work in the US

Requirements:

  • Preferred Languages and dbs: Python, PostgreSQL, MongoDB
  • Hands on experience working with NGS datasets
  • Strong experience and familiarity with standard bioinformatics tools, e.g. bwa, samtools, bedtools, gatk/mutec, etc.
  • Experience working with mutation and/or gene curation sources such as ClinVar, HGMD, OMIM, etc.
  • Preferred experience with designing or working with distributed architectures

To apply for this job email your details to humanresources@variantyx.com

Location:
Framingham – MA (remote work friendly)